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 Isaac Guerendo unlikely to play in Week 16
Hamstring injury
By: Mike Krueger | Thu Dec 19, 12:05 pm
|  | After losing RBs Christian McCaffrey, Jordan Mason and Elijah Mitchell to season-ending injuries, it now looks as if the 49ers will be without RB Isaac Guerendo for Sunday’s game vs. Miami. Guerendo is dealing with a hamstring injury and is unlikely to play, per source. (Adam Schefter on X)
FFToday's Take: The 49ers suffer yet another injury at the running back position. Patrick Taylor is next up on the depth chart and should get the bulk of work against the Dolphins. Ke’Shawn Vaughn and Israel Abanikanda are also on the roster but haven't been with the team for very long. Taylor is an acceptable Flex option in Week 16.
| Isaac Guerendo plans to play Thursday night
Questionable with foot injury
By: Mike Krueger | Thu Dec 12, 7:03 am
| | With the fantasy football playoffs starting tonight:
49ers rookie RB Isaac Guerendo plans to play Thursday night vs. the Rams despite his sprained foot that has left him being listed as questionable, per sources. Guerendo insists he “feels good.” (Adam Schefter on X)
FFToday's Take: It sounds like Guerendo is going to play in Week 15 against the Rams but how much he plays is a different question. The 49ers typically ride one running back, so if he's available he's likely to get plenty of work. Patrick Taylor is the next man up if Guerendo is Inactive for some reason or reaggravates his foot injury.
| Isaac Guerendo limited in practice Wednesday, Questionable
Foot injury
By: Mike Krueger | Wed Dec 11, 4:21 pm
| | 49ers ruled out LT Trent Williams (ankle) and S Malik Mustapha (chest, shoulder) for Thursday night’s game vs. the Rams.
DE Nick Bosa (hip, oblique), RB Isaac Guerendo (foot) and LB Dre Greenlaw (Achilles) are listed as questionable. (Adam Schefter on X)
FFToday's Take: Guerendo got in a limited practice Wednesday and is listed as Questionable for Thursday night against the Rams. If he lands on the inactive list, Patrick Taylor would slide into the starting running back role for the 49ers and see the bulk of work making him a solid RB2 play in Week 15.
| No practice for Isaac Guerendo on Tuesday
Exited Week 14 with a foot injury
By: Doug Orth | Tue Dec 10, 11:40 pm
| | Isaac Guerendo (foot) had his jersey on at practice and was walking around without a limp. But he was not taking part. 49ers will see how much progress he makes over the next two days. (The athletic - Matt Barrows)
FFToday's Take: Yet another instance in which a Thursday Night Football may not allow a player enough time to heal up. It is impossible to say with any certainty which way this will go, although Guerendo told reporters at some point after the game that he felt "great." San Francisco's practice schedule also tells us nothing because teams rarely do much more than a walk-through for a TNF game following a Sunday contest. Guerendo (or Patrick Taylor if the rookie sits) should be considered a serviceable RB2 against a Rams defense that just bottled up James Cook and held the 49ers' running game in check back in Week 3.
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